This can inflame as well as harm the inside layer of the esophagus even though noticeable symptoms of inflammation take place in a small number of patients.
The refluxed liquid may as well have bile that has backed-up into the stomach from duodenum.
Pepsin and bile may as well damage the esophagus, although their part in causing the esophageal inflammation and damage is not as intensive as that of acid.
The muscle that makes up the lower esophageal sphincter is usually active.
This closing of the passage stops reflux.
One is unusually weak contraction of the lower esophageal sphincter, which lessens its capacity to stop reflux.
These prolonged relaxations causes acid reflux to occur more easily.
This sac can trap acid coming from the stomach.
Therefore, it is easier for the acid to reflux as the lower esophageal sphincter relaxes with a swallow.
As the wave of contraction is defective, refluxed acid is not forced back into the stomach.
For example, waves of contraction may not start after every swallow or the waves of contraction may disappear before they reach the stomach.
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